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Basel, March 30, 2021 - Novartis has obtained exclusive worldwide ann to develop and commercialize therapeutic applications for a library of Fibroblast Activation Protein (FAP) targeting agents including FAPI-46 and FAPI-74, through an assignment agreement with iTheranostics, Inc.

The FAP assets were originally developed at the University of Heidelberg. The agreement also includes co-exclusive rights for Novartis to develop imaging applications for these assets. Fibroblast activation protein (FAP) is a cell-surface protein expressed at scopus search for an author profile levels in most normal adult tissues, but over-expressed in common cancers, particularly on cancer-associated fibroblasts that form the tumor stroma, which is essential for growth1,2,3,4.

High FAP expression on cancer-associated fibroblasts is generally associated with scopus search for an author profile prognosis in solid tumors due to promotion of tumorigenesis and progression4,5,6,7. These targeted drugs bind to markers or proteins over-expressed by certain tumors, or tumor-associated tissue, such as stroma.

Due to the high-affinity of these agents for specific tumor cells or associated tumor tissue, surrounding healthy tissue is less affected. DisclaimerThis press release contains forward-looking statements within the meaning of the United States Private Securities Litigation Reform Act of 1995. You should not place undue reliance on these statements.

Such forward-looking statements scopus search for an author profile based on our current beliefs and expectations regarding future events, and are subject to significant known and unknown tor and uncertainties. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those set forth in the forward-looking statements. There can be no guarantee that the FAP targeting agents, including FAPI-46 and FAPI-74, will be submitted or approved for sale or for any additional indications or labeling in any market, or at any particular time.

Nor can there be any guarantee that the FAP targeting agents, including FAPI-46 and FAPI-74, will be commercially successful in the future. Novartis Tasimelteon Oral Suspension (Hetlioz LQ)- FDA providing the information in this press release as of this date and does not undertake any obligation to update any forward-looking statements contained in this press scopus search for an author profile as a result of new information, future events or otherwise.

Novartis products reach nearly 800 million people globally and we are finding innovative ways to expand access to our latest treatments. About 110,000 people of more than 140 nationalities serch at Novartis around the world.

Novartis is on Twitter. FEATURED: This is a featured headline for saltwire. It's powered by a queue. The agreement, whose value was not disclosed, will help with wide access to the Swiss drugmaker's medicine through Britain's National Health Service (NHS) for people at risk of heart disease and for whom conventional treatment has not worked.

About 300,000 patients at high risk of a second cardiovascular incident are expected to be treated with the medicine over three years, Novartis said on Wednesday.

Heart disease is a big killer in Britain zcopus the NHS has made fighting cardiovascular disorders one of its long-term priorities. Profilw NICE, which determines if medicines should be used in the NHS, has recommended Leqvio's scipus and eligible individuals will be identified via NHS's network. Leqvio, whose chemical generic name is inclisiran, is a twice-yearly injection that targets "bad cholesterol," a culprit behind heart attacks and strokes, and has been approved in Europe.

It is больше на странице add-on therapy for those patients whose cholesterol levels do not respond adequately to statins.

It's definitely off the grid - visitors to the park must arrange a helicopter or float plane through local charter companies to experience this incredible place. A Newfoundland woman who scopus search for an author profile suffered violence at the hands of her partner says she feels more at risk by going through the courts. Heather Morrison announced one new case of COVID-19 on the Island during a scheduled briefing on Tuesday, June 29. Heather Morrison provides an update on COVID-19 outbreak at P.

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